Cascara sagrada is the dried bark of a small tree that grows in the Pacific Northwest. Available in capsules, liquid extract and tea, cascara sagrada functions as a laxative, and people take it to relieve occasional constipation.
Stomach Upset
The most common side effect associated with cascara sagrada is upset stomach. Other side effects include abdominal cramps and nausea.
Diarrhea
Because of the laxative effect, cascara sagrada can cause diarrhea, which in turn can result in fluid and electrolyte imbalances, and vitamin and mineral deficiencies.
Constipation
As with other laxatives, chronic use of cascara sagrada can cause dependency, causing constipation unless using the medication. People should not use cascara sagrada longer than seven consecutive days.
Melanosis Coli
Chronic use of cascara sagrada also can cause a condition called melanosis coli, which involves staining or darkening of the colonic mucosa. This usually is not a serious side effect, but it can reduce bowel function.
Urine Color
Cascara sagrada can change the color of urine to pink, red, violet, brown or black.
Considerations
People with certain health conditions should not take cascara sagrada. These include appendicitis, Crohn's disease, diverticular disease, rectal bleeding, ulcerative colitis or a history of intestinal blockage.
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